Central Serous Chorioretinopathy Treatments: A Mini Review

Central serous chorioretinopathy (CSC) is a retinal disorder that primarily affects young (20to 50-year-old) white men, although it is seen occasionally in older patients and females. CSC is characterized by avascular focal leakage through the retinal pigment epithelium (RPE), resulting in serous detachment of the neurosensory retina. The course is usually self-limiting and in most cases resolves spontaneously within a 3-month period, with visual acuity usually recovering to 20/30 or better. However, chronic CSC may develop as a consequence of recurrences or persistent neurosensory detachment, and can result in progressive RPE atrophy and permanent visual loss. A primary involvement of the RPE and choroidal vascularization play a significant role in the pathogenesis of CSC and the current treatment options attempt to restore the functions of the RPE and the normal choroidal vasculature. The aim of the current review is to provide an overview of the current therapeutical approaches to CSC, including observation, laser treatment, Received: October 6, 2015 Accepted: October 6, 2015 Published online: December 1, 2015 Pierluigi Iacono Fondazione G.B. Bietti per l’Oftalmologia IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico) via Livenza 3, IT–00198 Rome (Italy) E-Mail pierluigi.iacono @ libero.it © 2015 S. Karger AG, Basel 0030–3747/15/0552–0076$39.50/0